Illnesses linked to trichloroethylene aka TCE aka TRIKE
CAS number: 79-01-6
Diseases linked to this toxicant grouped by strength of evidence.
Strong Evidence
- Acute hepatocellular injury (hepatitis)*
Good Evidence
- Acute tubular necrosis
- Arrhythmias
- Autoimmune antibodies (positive ANA, anti-DNA, RF, etc.)*
- Cardiac congenital malformations*
- Childhood leukemias
- Cirrhosis*
- Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span) / mental retardation / developmental delay*
- Decreased coordination / dysequilibrium
- Fetotoxicity (miscarriage / spontaneous abortion, stillbirth)*
- Hearing loss*
- Hepatocellular cancer (liver cancer)*
- Lymphoma (non-Hodgkin’s)*
- Psychiatric disturbances (disorientation, hallucinations, psychosis, delirium, paranoias, anxiety/depression, emotional lability, mood changes, euphoria)*
- Renal (kidney) cancer*
- Scleroderma
- Trigeminal neuropathy
Limited Evidence
- ADD/ADHD, hyperactivity*
- Adult-onset leukemias*
- Brain cancer – adult*
- Breast cancer*
- Cervical cancer
- Choanal atresia
- Genito-urinary malformations (includes male and female)
- Hodgkin’s disease (lymphoma)*
- Immune suppression
- Low birth weight / small for gestational age / intra-uterine growth retardation
- Lung cancer*
- Multiple myeloma*
- Nephrotic syndrome
- Neural tube defects / CNS malformations
- Oral clefts (cleft lip and palate)
- Pancreatic cancer*
- Pancreatitis
- Peripheral neuropathy*
- Prostate cancer*
- Raynaud’s phenomenon
- Systemic lupus erythematosus*
- Testicular cancer*
Illnesses marked thus * have been suffered by Irish Air Corps personnel or their offspring.
